Enhancement by glucose of the inhibition of an Ehrlich ascites tumor by tetraazatricyclododecane.

been found (9) although large doses have recently produced suggestive results (14). No effect of glucose on the inhibition of tumor growth in mice by a diazoamino compound was observed (26). It was later found that acidity failed to alter the inhibition of cell division by this compound (27, 28), which may help to explain the observed ineffectiveness of glucose. Acidity in the fluid surrounding cells often alters the effect on them of the weak acids and bases that dissociate in the pH range under consideration (5 to 8), e.g., phenols, amines, sul fonamides, as well as the effect of many compounds that